Ciudad de Panamá, Panama’s dynamic capital, fuses sleek skyscrapers with UNESCO Casco Viejo’s colonial charm. Stroll cobblestone streets to Plaza de la Independencia, explore Panama Canal’s Miraflores Locks, savor ceviche in multicultural markets. Biomuseo’s biodiversity, Cinta Costera sunset runs. Tropical 24–32°C; dry Dec–Apr ideal for clear skies and outdoor festivals.